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急性剂量酒精对精神运动表现的“宿醉”效应研究。

Investigation of the "hangover" effects of an acute dose of alcohol on psychomotor performance.

作者信息

Lemon J, Chesher G, Fox A, Greeley J, Nabke C

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.

出版信息

Alcohol Clin Exp Res. 1993 Jun;17(3):665-8. doi: 10.1111/j.1530-0277.1993.tb00816.x.

DOI:10.1111/j.1530-0277.1993.tb00816.x
PMID:8333598
Abstract

Performance on some complex and difficult tasks has been shown to be negatively affected for some time after an acute dose of alcohol has been cleared from the system. However, Dauncey reported impairment of a relatively simple reaction time task 3 hr after a dose of alcohol, when the blood alcohol concentration was at or near 0. This impairment was positively related to the subject's drinking history. A replication using the same task found a linear dose/impairment relationship during intoxication. A second simple reaction time task and a vigilance task showed a trend toward impairment, but only a divided attention task was significantly affected during intoxication. There was no significant effect of dose on any of these tests during a "morning after" session. The results are discussed in relation to the differences in method between Dauncey and this study.

摘要

研究表明,在急性摄入的酒精从体内清除后的一段时间内,执行某些复杂且困难任务的表现会受到负面影响。然而,当血液酒精浓度处于或接近0时,丹西报告称在摄入一剂酒精3小时后,一项相对简单的反应时间任务出现了损伤。这种损伤与受试者的饮酒史呈正相关。使用相同任务进行的重复研究发现,在醉酒期间存在线性剂量/损伤关系。另一项简单反应时间任务和一项警觉任务显示出损伤趋势,但在醉酒期间只有一项注意力分散任务受到了显著影响。在“宿醉”期间,剂量对这些测试中的任何一项均无显著影响。文中结合丹西的研究与本研究在方法上的差异对结果进行了讨论。

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