Mohr U, Reznik G, Emminger E, Lijinsky W
J Natl Cancer Inst. 1977 Feb;58(2):429-32. doi: 10.1093/jnci/58.2.429.
Pancreatic duct carcinomas were induced in Syrian hamsters by intragastric administration of 2,6-dimethylnitrosomorpholine. As early as 30 weeks after treatment began, tumors were macroscopically visible in the pancreas; the maximum incidence of such tumors reached 71% by the end of the experiment. They were ductal in origin, and some metastasized to the lung. They were identified histologically as adenomas and carcinomas and developed in different parts of the organ without demonstrating any preferred localization.
通过给叙利亚仓鼠灌胃2,6-二甲基亚硝基吗啉诱导胰腺导管癌。早在治疗开始30周后，胰腺中就可肉眼见到肿瘤；到实验结束时，此类肿瘤的最高发生率达到71%。它们起源于导管，有些转移至肺。组织学上它们被鉴定为腺瘤和癌，在胰腺的不同部位发生，未表现出任何特定的定位倾向。
