Kullavanijaya P, Sirimachan S, Bhuddhavudhikrai P
Department of Medical Services, Ministry of Public Health, Bangkok, Thailand.
Int J Dermatol. 1993 Jul;32(7):504-7. doi: 10.1111/j.1365-4362.1993.tb02834.x.
Non-tuberculous mycobacterial (NTB) infections are not commonly diagnosed in Thailand. The dissertation of reported cases among 10 published reports of 44 cases within 20 years revealed only six cases of cutaneous infections in which M. marinum was not included.
The proven cases of M. marinum infection were studied at the Institute of Dermatology, Bangkok from 1981 to 1990. The clinical data, histopathology, tuberculin test, chest x-ray, and treatments were recorded.
M. marinum skin infection accounted for 18 cases (81.8% of NTB skin infection), 10 men and 8 women. A history of preceding trauma occurred in 11 cases (61.1%), most of which were negligible wounds or minor abrasions. Twelve cases (66.7%) were in contact with organisms in their occupations and hobbies associated with fish and water exposure.
Eighteen cases of M. marinum cutaneous infection acquired from occupations and hobbies were reported. The term "M. marinum cutaneous infection" or "M. marinum granuloma" instead of swimming pool granuloma or fish tank granuloma was proposed. According to this study, cotrimoxazole was the most appropriate drug for the treatment of M. marinum cutaneous infection.
非结核分枝杆菌（NTB）感染在泰国并不常见。对20年内发表的10篇报告中44例报告病例的分析显示，仅有6例皮肤感染病例未包括海鱼分枝杆菌。
1981年至1990年在曼谷皮肤病研究所对确诊的海鱼分枝杆菌感染病例进行研究。记录临床数据、组织病理学、结核菌素试验、胸部X线检查及治疗情况。
海鱼分枝杆菌皮肤感染18例（占NTB皮肤感染的81.8%），男性10例，女性8例。11例（61.1%）有先前创伤史，多数为轻微伤口或擦伤。12例（66.7%）在与其职业及与接触鱼和水相关的爱好中接触到病原体。
报告了18例因职业和爱好而感染海鱼分枝杆菌的皮肤感染病例。建议使用“海鱼分枝杆菌皮肤感染”或“海鱼分枝杆菌肉芽肿”这一术语，而非游泳池肉芽肿或鱼缸肉芽肿。根据本研究，复方新诺明是治疗海鱼分枝杆菌皮肤感染最适宜的药物。
