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拉氏新孢霉和拉氏新孢醇a,来自子囊菌纸状拉氏新孢霉(Karst.)Karst.的具有杀线虫和抗菌活性的新代谢产物。II. 结构解析。

Lachnumon and lachnumol a, new metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. II. Structural elucidation.

作者信息

Stadler M, Anke H, Bergquist K E, Sterner O

机构信息

University of Kaiserslautern, Department of Biotechnology, Germany.

出版信息

J Antibiot (Tokyo). 1993 Jun;46(6):968-71. doi: 10.7164/antibiotics.46.968.

DOI:10.7164/antibiotics.46.968
PMID:8344879
Abstract

The structures of two new biologically active chlorinated metabolites isolated from submerged cultures of the ascomycete Lachnum papyraceum have been elucidated by NMR and mass spectroscopy. The compounds, lachnumon (1) and lachnumol A (2), which structurally are related with mycorrhizin A that also is produced by the fungus, contain an unusual chlorinated epoxide group.

摘要

从子囊菌纸质腊壳菌的深层培养物中分离出的两种新的具有生物活性的氯化代谢产物的结构已通过核磁共振和质谱分析得以阐明。化合物腊壳菌素(1)和腊壳菌醇A(2)在结构上与该真菌产生的菌根菌素A相关,它们含有一个不寻常的氯化环氧基团。

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