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来自子囊菌纸质腊壳菌(Karst.)Karst.的具有杀线虫和抗菌活性的新代谢产物。VII. 溴化腊壳菌素和菌根菌素A衍生物的结构测定

New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. VII. Structure determination of brominated lachnumon and mycorrhizin A derivatives.

作者信息

Stadler M, Anke H, Sterner O

机构信息

University of Kaiserslautern, Department of Biotechnology, Germany.

出版信息

J Antibiot (Tokyo). 1995 Feb;48(2):158-61. doi: 10.7164/antibiotics.48.158.

DOI:10.7164/antibiotics.48.158
PMID:7706127
Abstract

The structure determination of lachnumon B1 (16) and lachnumon B2 (17), brominated derivatives of lachnumon (1), as well as mycorrhizin B1 (18) and mycorrhizin B2 (19), brominated derivatives of mycorrhizin A (3), is described. The compounds, which exhibit similar antimicrobial and nematicidal activity as their chlorinated analogues, were isolated from extracts of cultures of the ascomycete Lachnum papyraceum to which CaBr2 had been added. The structures were elucidated by spectroscopic methods.

摘要

描述了乳盘菌素B1(16)和乳盘菌素B2(17)(乳盘菌素(1)的溴化衍生物)以及菌根菌素B1(18)和菌根菌素B2(19)(菌根菌素A(3)的溴化衍生物)的结构测定。这些化合物与其氯化类似物表现出相似的抗菌和杀线虫活性,它们是从添加了CaBr2的子囊菌纸状乳盘菌培养物的提取物中分离得到的。通过光谱方法阐明了其结构。

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