Stadler M, Anke H, Sterner O
University of Kaiserslautern, Department of Biotechnology, Germany.
J Antibiot (Tokyo). 1995 Feb;48(2):158-61. doi: 10.7164/antibiotics.48.158.
The structure determination of lachnumon B1 (16) and lachnumon B2 (17), brominated derivatives of lachnumon (1), as well as mycorrhizin B1 (18) and mycorrhizin B2 (19), brominated derivatives of mycorrhizin A (3), is described. The compounds, which exhibit similar antimicrobial and nematicidal activity as their chlorinated analogues, were isolated from extracts of cultures of the ascomycete Lachnum papyraceum to which CaBr2 had been added. The structures were elucidated by spectroscopic methods.
描述了乳盘菌素B1(16)和乳盘菌素B2(17)(乳盘菌素(1)的溴化衍生物)以及菌根菌素B1(18)和菌根菌素B2(19)(菌根菌素A(3)的溴化衍生物)的结构测定。这些化合物与其氯化类似物表现出相似的抗菌和杀线虫活性,它们是从添加了CaBr2的子囊菌纸状乳盘菌培养物的提取物中分离得到的。通过光谱方法阐明了其结构。