Stadler M, Anke H, Shan R, Sterner O
University of Kaiserslautern, Department of Biotechnology, Germany.
J Antibiot (Tokyo). 1995 Feb;48(2):154-7. doi: 10.7164/antibiotics.48.154.
The structure determination of four new biologically active non-halogenated metabolites isolated from submerged cultures of the ascomycete Lachnum papyraceum is described. The compounds are structurally related to the antibiotic mycorrhizin A: (l'Z)-Dechloromycorrhizin A (12), a stereoisomer of dechloromycorrhizin A (5) previously isolated from the same fungus, as well as papyracon A (13), papyracon B (14) and papyracon C (15) containing an exocyclic double bond. The amounts of the latter three increased significantly when CaBr2 was added to the culture medium. The structures were determined by spectroscopic methods.
描述了从子囊菌纸质腊壳菌的深层培养物中分离出的四种新的具有生物活性的非卤代代谢产物的结构测定。这些化合物在结构上与抗生素菌根菌素A相关：（1'Z）-脱氯菌根菌素A（12），它是先前从同一真菌中分离出的脱氯菌根菌素A（5）的立体异构体，以及含有环外双键的纸质腊壳菌素A（13）、纸质腊壳菌素B（14）和纸质腊壳菌素C（15）。当向培养基中添加CaBr2时，后三种化合物的量显著增加。通过光谱方法确定了其结构。
