Stadler M, Anke H, Arendholz W R, Hansske F, Anders U, Sterner O, Bergquist K E
Universität Kaiserslautern, Lehrbereich Biotechnologie, Fed. Rep. Germany.
J Antibiot (Tokyo). 1993 Jun;46(6):961-7. doi: 10.7164/antibiotics.46.961.
Several chlorinated metabolites with nematicidal, antimicrobial, and cytotoxic activities were isolated from submerged cultures of the ascomycete Lachnum papyraceum. Three compounds were identified as (+)-mycorrhizin A (3), (+)-chloromycorrhizin A (4) and (+)-dechloromycorrhizin A (5). The occurrence of 5 as a natural product is new. Two compounds, lachnumon (1) and lachnumol A (2), were found to be new fungal metabolites with cytotoxic, nematicidal and antimicrobial activities.
从子囊菌纸状垂幕菇的深层培养物中分离出了几种具有杀线虫、抗菌和细胞毒性活性的氯化代谢产物。三种化合物被鉴定为(+)-菌根菌素A(3)、(+)-氯菌根菌素A(4)和(+)-脱氯菌根菌素A(5)。5作为一种天然产物的出现是新的。两种化合物,垂幕菌素(1)和垂幕醇A(2),被发现是具有细胞毒性、杀线虫和抗菌活性的新型真菌代谢产物。