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从腹泻患者分离出的拟态弧菌菌株中耐热直接溶血素（TDH）样毒素的高流行率。

High prevalence of thermostable direct hemolysin (TDH)-like toxin in Vibrio mimicus strains isolated from diarrhoeal patients.

作者信息

Uchimura M, Koiwai K, Tsuruoka Y, Tanaka H

机构信息

Public Health Laboratory of Chiba Prefecture, Japan.

出版信息

Epidemiol Infect. 1993 Aug;111(1):49-53. doi: 10.1017/s0950268800056661.

DOI:10.1017/s0950268800056661
PMID:8348932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2271200/
Abstract

A total of 17 isolates of Vibrio mimicus from patients, 29 from environment and 2 from food was examined for toxigenicity. Sixteen (94%) clinical isolates and one (50%) from food produced TDH-like toxin, whereas none of the environmental isolates did so. The food from which V. mimicus with TDH-like toxin production was isolated, was one which had caused food poisoning. Only one environmental strain produced CT-like toxin, whilst ST-like toxin was not detected from any strains tested.

摘要

对从患者身上分离出的17株拟态弧菌、从环境中分离出的29株以及从食品中分离出的2株进行了产毒检测。16株（94%）临床分离株和1株（50%）食品分离株产生了类TDH毒素，而环境分离株均未产生。分离出产生类TDH毒素的拟态弧菌的食品曾导致食物中毒。仅1株环境菌株产生了类CT毒素，而在所检测的任何菌株中均未检测到类ST毒素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d39/2271200/da63c3ba0b77/epidinfect00040-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d39/2271200/da63c3ba0b77/epidinfect00040-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d39/2271200/da63c3ba0b77/epidinfect00040-0058-a.jpg

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本文引用的文献

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Characterization of biochemically atypical Vibrio cholerae strains and designation of a new pathogenic species, Vibrio mimicus.生化特性不典型的霍乱弧菌菌株的鉴定及新致病物种拟态弧菌的命名
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Disease from infection with Vibrio mimicus, a newly recognized Vibrio species. Clinical characteristics and edipemiology.由拟态弧菌（一种新发现的弧菌属菌种）感染引起的疾病。临床特征与流行病学。
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Medium-dependent production of extracellular enterotoxins by non-O-1 Vibrio cholerae, Vibrio mimicus, and Vibrio fluvialis.
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Studies on the enteropathogenic, facultatively halophilic bacterium, Vibrio parahaemolyticus. 3. Enteropathogenicity.关于肠道致病性兼性嗜盐菌副溶血性弧菌的研究。3. 肠道致病性。
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Development of a highly sensitive bead-ELISA to detect bacterial protein toxins.
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