Raz I, Levinger S, Maravi Y, Sigelmann N, Shananas M, Bursztyn M
Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.
Isr J Med Sci. 1993 Jun-Jul;29(6-7):347-50.
The prevalence of intolerance to glucose was compared between young immigrant Ethiopian Jews shortly after their arrival to Israel, a similar group of Ethiopians 2-3 years after their arrival to Israel, and young Israeli students. A relatively high prevalence of glucose intolerance was found in both Ethiopian groups, but we could not demonstrate any deterioration in glucose tolerance after 2-3 years of Israeli life-style in the Ethiopian groups. In spite of high blood glucose levels in response to 75 g glucose load, when compared to Israeli students the Ethiopians' fasting insulin levels and insulin response to 75 g of glucose was relatively low, suggesting a higher glucose threshold for insulin secretion. However, in the Ethiopians, impaired glucose tolerance was associated with hyperinsulinemia, suggesting that similar to some other populations glucose intolerance is associated with insulin resistance.
对刚抵达以色列的年轻埃塞俄比亚犹太移民、抵达以色列2 - 3年后的类似埃塞俄比亚人群组以及年轻的以色列学生进行了葡萄糖不耐受患病率的比较。在两个埃塞俄比亚人群组中均发现葡萄糖不耐受的患病率相对较高，但我们未能证明埃塞俄比亚人群组在采用以色列生活方式2 - 3年后葡萄糖耐量有任何恶化。尽管在75克葡萄糖负荷试验中血糖水平较高，但与以色列学生相比，埃塞俄比亚人的空腹胰岛素水平以及对75克葡萄糖的胰岛素反应相对较低，这表明胰岛素分泌的葡萄糖阈值较高。然而，在埃塞俄比亚人中，糖耐量受损与高胰岛素血症相关，这表明与其他一些人群类似，葡萄糖不耐受与胰岛素抵抗有关。
