Raz I, Chigier E, Rosenblit H, Mevorach R, Bursztyn M
Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.
Isr J Med Sci. 1993 Jun-Jul;29(6-7):351-4.
The prevalence of glucose intolerance and hypertension was compared between a group of 87 young Ethiopian males (age 21.6 +/- 2.8 years) from the post Moses immigration of 1989 (group 1) and 89 age-matched Ethiopian males (age 21.4 +/- 3.1) from the Solomon immigration of 1991 (group 2). Both groups demonstrated a relatively high, for age, prevalence of glucose intolerance: 5% and 8% in groups 1 and 2 respectively (not significant). However, group 1 had a higher glucose level 2 h after an oral glucose tolerance test (P < 0.05) and a higher level of HbA1C (P < 0.05) and fructosamine (P = 0.07), concomitant with a lower fasting insulin (P < 0.005), when compared with group 2. Group 2 had a significant increase in both systolic and diastolic blood pressure when compared with group 1 (P < 0.05, P < 0.005 respectively). Group 2 had higher blood pressure levels and higher fasting insulin than group 1, suggesting a relationship between insulin levels and blood pressure in this population.
对1989年摩西移民潮后的87名年轻埃塞俄比亚男性(年龄21.6±2.8岁)(第1组)和1991年所罗门移民潮中的89名年龄匹配的埃塞俄比亚男性(年龄21.4±3.1岁)(第2组)的葡萄糖不耐受和高血压患病率进行了比较。两组在同龄人中葡萄糖不耐受的患病率相对较高:第1组和第2组分别为5%和8%(无显著差异)。然而,与第2组相比,第1组在口服葡萄糖耐量试验后2小时血糖水平更高(P<0.05),糖化血红蛋白(HbA1C)水平更高(P<0.05),果糖胺水平更高(P=0.07),同时空腹胰岛素水平更低(P<0.005)。与第1组相比,第2组的收缩压和舒张压均显著升高(分别为P<0.05,P<0.005)。第2组的血压水平和空腹胰岛素水平高于第1组,表明该人群中胰岛素水平与血压之间存在关联。