Hansen S R, Janssen C, Beasley V R
Zoecon Corporation, Dallas, TX 75234.
Vet Hum Toxicol. 1993 Jun;35(3):234-6.
When ingested at 10 ppm by human beings, denatonium benzoate has an extremely bitter, unpleasant taste. The addition of denatonium benzoate to liquid dish detergents and orange juice reduces the amount ingested by children. The toxicity of denatonium benzoate is low with acute po LD50's in rats of 485-740 mg/kg. The use of bittering agents, such as denatonium benzoate, could reduce the ingestion of toxic substances by dogs, cats, other animals and children and warrants further investigation.
当人类以10 ppm的浓度摄入苯甲地那铵时，会有极其苦涩、令人不适的味道。在液体餐具洗涤剂和橙汁中添加苯甲地那铵可减少儿童的摄入量。苯甲地那铵的毒性较低，大鼠急性经口半数致死量为485 - 740 mg/kg。使用苦味剂，如苯甲地那铵，可能会减少狗、猫、其他动物和儿童摄入有毒物质的情况，值得进一步研究。
