Teschke K, Kelly S J, Wiens M, Hertzman C, Dimich-Ward H, Ward J E, Van Oostdam J C
Department of Health Care and Epidemiology, University of British Columbia, Vancouver.
Can J Public Health. 1993 May-Jun;84(3):192-6.
Adipose tissue from a sample of 41 British Columbians was analyzed for a number of organochlorine pesticides. Pesticide concentrations were very low. Persistent fat-soluble compounds like DDT were found at the highest concentrations, whereas compounds that either quickly metabolize to other forms or are readily excreted were found at low levels or not detected. Data on age, sex, area of residence, occupation, diet and weight were obtained by interview. Increasing age was related to increasing levels of several of the persistent pesticides. Although there were insufficient data for statistical analysis, two individuals with potential occupational exposures had much higher levels of the pesticides than other subjects. Although population-based surveys of these organochlorine pesticides in human tissue may have little value, further study may be warranted for groups known to have had high exposures (e.g. occupationally exposed).
对41名不列颠哥伦比亚人的脂肪组织样本进行了多种有机氯农药分析。农药浓度非常低。像滴滴涕这样的持久性脂溶性化合物浓度最高,而那些能迅速代谢为其他形式或易于排泄的化合物浓度较低或未被检测到。通过访谈获取了年龄、性别、居住地区、职业、饮食和体重数据。年龄增长与几种持久性农药水平的增加有关。尽管数据不足以进行统计分析,但两名有潜在职业暴露的个体的农药水平比其他受试者高得多。尽管基于人群的人体组织中这些有机氯农药调查可能价值不大,但对于已知有高暴露风险的人群(如职业暴露人群),可能有必要进行进一步研究。