Saraswat B, Visen P K, Patnaik G K, Dhawan B N
ICMR Centre for Advanced Pharmacological Research on Traditional Remedies, Division of Pharmacology, Lucknow, India.
Indian J Exp Biol. 1993 Apr;31(4):316-8.
Picroliv showed a dose (3-12 mg/kg, po for 7 days) dependent choleretic activity as evidenced by increase in bile flow and its contents (bile salts and bile acids). Significant anticholestatic activity was also observed against carbon tetrachloride induced cholestasis in conscious rat, anaesthetized guinea pig and cat. Picroliv was more active than the known hepatoprotective drug silymarin.
