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产朊假丝酵母葡甘露聚糖。结构研究。

Glucomannan from Candida utilis. Structural investigation.

作者信息

Kogan G, Sandula J, Simkovicová V

机构信息

Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia.

出版信息

Folia Microbiol (Praha). 1993;38(3):219-24. doi: 10.1007/BF02814381.

DOI:10.1007/BF02814381
PMID:8365697
Abstract

Structure of the glucomannan isolated from the cell walls of Candida utilis has been investigated using acetolysis fragmentation, methylation analysis and NMR spectroscopy. The structure of the glucomannan resembles that of the cellular mannans of other Candida species, except that the longer tetra- and pentassacharide side-chains are terminated with a glucosyl residue. Presence of the nonreducing glucosyl groups at the ends of the side-chains caused the C. utilis not to cross-react in a double immunodiffusion test with other Candida species that possess mannan antigens and cross-react with Hansenula species with glucomannan antigens.

摘要

已通过乙酰解片段化、甲基化分析和核磁共振光谱法对从产朊假丝酵母细胞壁中分离出的葡甘露聚糖的结构进行了研究。该葡甘露聚糖的结构与其他假丝酵母属的细胞甘露聚糖相似,只是较长的四糖和五糖侧链以一个葡萄糖基残基结尾。侧链末端存在非还原性葡萄糖基导致产朊假丝酵母在双向免疫扩散试验中不与其他具有甘露聚糖抗原的假丝酵母属发生交叉反应,也不与具有葡甘露聚糖抗原的汉逊酵母属发生交叉反应。

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Studies on the antitumor polysaccharides, especially a mannan preparation derived from Candida utilis--a review.抗肿瘤多糖的研究,特别是来自产朊假丝酵母的一种甘露聚糖制剂——综述。
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Structural studies of mannans from the cell walls of the pathogenic yeasts Candida albicans serotypes A and B and Candida parapsilosis.致病性酵母白色念珠菌A和B血清型以及近平滑念珠菌细胞壁中甘露聚糖的结构研究。
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Novel structure of the cellular mannan of the pathogenic yeast Candida krusei.致病性酵母克鲁斯假丝酵母的细胞甘露聚糖的新结构
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Structure and biosynthesis of the mannan component of the yeast cell envelope.酵母细胞包膜甘露聚糖成分的结构与生物合成
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