de la Puente M L, Corio R, Alvarez J, Planas C, Isalt R, Marzo M
Departament de Sanitat i Seguretat Social, Generalitat de Catalunya.
Aten Primaria. 1993 Sep 15;12(4):205-6, 208-10.
Analysis of an outbreak of measles among a partially vaccinated school population: the epidemiology, the effectiveness of the control measures and the efficacy of the vaccine (EV).
A descriptive study and cohorts study.
Primary Care in the borough of Sant Andreu de la Barca.
The school population of Sant Andreu de la Barca.
The outbreak lasted three months and twenty days, with 95 cases overall. The most affected age group was form 4 to 10. 8.4% presented complications. Children were infected at school in 87% of the cases. The overall infection rate of the population between 0 and 15 was 2.4%. 36% of the cases had been correctly immunized and 43% were preventable cases. Vaccine coverage contacts was 67%. 84% of the susceptible contacts were vaccinated. Immunization status and immunization age of 323 out of 500 pupils was studied for the EX analysis. Global EV was 66% (42-80), 58% (13-80) for those immunized, between 12-14 month of age and 71% (43-85) for those immunized after the 15 month of age.
In order to eradicate the autoctonous measles an increase in immunization coverage, an improvement in the epidemiologic surveillance, and in the outbreak control measures are needed.
分析部分接种疫苗的在校人群中麻疹暴发情况:流行病学、控制措施的有效性及疫苗效力(EV)。
描述性研究和队列研究。
圣安德鲁-德拉巴尔卡区的初级保健机构。
圣安德鲁-德拉巴尔卡区的在校人群。
疫情持续了三个月零二十天,共95例病例。受影响最严重的年龄组为4至10岁。8.4%出现并发症。87%的病例是在学校感染的。0至15岁人群的总体感染率为2.4%。36%的病例接种正确,43%为可预防病例。疫苗接种覆盖率为67%。84%的易感接触者接种了疫苗。对500名学生中的323名进行了疫苗效力分析的免疫状态和免疫年龄研究。总体疫苗效力为66%(42 - 80),12至14月龄接种疫苗者为58%(13 - 80),15月龄后接种疫苗者为71%(43 - 85)。
为根除本地麻疹,需要提高免疫接种覆盖率、改善流行病学监测及疫情控制措施。