Collins J A, Burrows E A, Willan A R
Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Fertil Steril. 1993 Sep;60(3):477-85.
To evaluate the influence of socioeconomic factors on the outcomes of infertility, including pregnancy, adoption, resolution, and loss to follow-up.
Prospective observational study.
Infertility clinics in 11 teaching hospitals.
Newly registered couples with infertility of > 1 year.
Demographic, clinical, and occupational data were recorded at registration, and events including treatment, pregnancy, adoption, and resolution were recorded during up to 7 years of follow-up.
Time to outcomes was evaluated by means of proportional hazards analyses with respect to the occurrence of conception of livebirth, adoption, resolution, or loss to follow-up.
[1] The clinical predictors of pregnancy included duration of infertility, pregnancy history, female partner's age, diagnosis of tubal defect or endometriosis, and treatment; [2] the likelihood of livebirth was 1.38 times greater in partnerships with a male professional; [3] adoption was 1.64 times more likely with male professional partners; [4] loss to follow-up was 1.61 times more likely if the female partner was unemployed; and [5] the likelihood of resolution was unrelated to occupation or income variables.
Socioeconomic factors, as expressed by occupation, are significantly associated with important outcomes among infertile couples.
评估社会经济因素对不孕结局的影响，包括妊娠、领养、问题解决及失访情况。
前瞻性观察研究。
11家教学医院的不孕不育诊所。
新登记的不孕不育时间超过1年的夫妇。
登记时记录人口统计学、临床及职业数据，在长达7年的随访期间记录包括治疗、妊娠、领养及问题解决等事件。
通过比例风险分析评估活产受孕、领养、问题解决或失访发生时的结局时间。
[1]妊娠的临床预测因素包括不孕持续时间、妊娠史、女性伴侣年龄、输卵管缺陷或子宫内膜异位症诊断及治疗情况；[2]男性为专业人员的伴侣活产可能性高1.38倍；[3]男性为专业人员的伴侣领养可能性高1.64倍；[4]女性伴侣失业时失访可能性高1.61倍；[5]问题解决的可能性与职业或收入变量无关。
职业所体现的社会经济因素与不孕夫妇的重要结局显著相关。
