Labuda M, Nuttall P A, Kozuch O, Elecková E, Williams T, Zuffová E, Sabó A
Institute of Virology, Slovak Academy of Sciences, Bratislava.
Experientia. 1993 Sep 15;49(9):802-5. doi: 10.1007/BF01923553.
The vectors of arthropod-borne viruses (arboviruses) become infected by feeding on the viraemic blood of an infected animal. This theory is based on transmission studies involving artificial infection of vertebrate hosts by syringe inoculation. To reproduce natural conditions of virus transmission, infected and uninfected vectors (ticks) of tick-borne encephalitis virus, the most important arbovirus in Europe, were allowed to feed together on uninfected wild vertebrate hosts. The greatest numbers of infected ticks were obtained from susceptible host species that had undetectable or very low levels of viraemia. The results suggest that 'nonviremic transmission' is an important mechanism for the survival of certain arboviruses in nature.
节肢动物传播病毒（虫媒病毒）的媒介通过吸食受感染动物的病毒血症血液而被感染。这一理论基于涉及通过注射器接种对脊椎动物宿主进行人工感染的传播研究。为了重现病毒传播的自然条件，让欧洲最重要的虫媒病毒——蜱传脑炎病毒的感染和未感染媒介（蜱）一起吸食未感染的野生脊椎动物宿主。从病毒血症检测不到或水平极低的易感宿主物种中获得了数量最多的感染蜱。结果表明，“非病毒血症传播”是某些虫媒病毒在自然界中生存的重要机制。
