Jeret J S, Mandell M, Anziska B, Lipitz M, Vilceus A P, Ware J A, Zesiewicz T A
Department of Neurology, SUNY Health Science Center, Brooklyn.
Neurosurgery. 1993 Jan;32(1):9-15; discussion 15-6. doi: 10.1227/00006123-199301000-00002.
We prospectively studied 712 consecutive patients during a 1-year period who presented with amnesia or loss of consciousness after nonpenetrating head trauma and who had a perfect Glasgow Coma Scale score of 15. Of the 67 (9.4%) patients with acute traumatic lesions disclosed by computed tomography (CT) of the head, 2 required neurosurgical intervention and 1 died. Four factors were statistically correlated (P < 0.05) with abnormal CT findings: Older age, white race, signs of basilar skull fracture, and being either a pedestrian hit by a motor vehicle or a victim of an assault. Sex, length of antero- or retrograde amnesia, forward and reverse digit spans, object recall, focal abnormality on the general neurological exam, and subjective complaints were not statistically correlated with CT abnormality. Using step-wise discriminant function analysis, no single item or combination of items could be used to classify 95% of the patients into either the normal or abnormal CT group. Therefore, regardless of age, mechanism of injury, or clinical findings, intracranial lesions cannot be completely excluded clinically on head-trauma patients who have loss of consciousness or amnesia, even if the Glasgow Coma Scale score is 15. However, only two patients (0.3%) required neurosurgical intervention.
我们前瞻性地研究了在1年期间连续收治的712例非穿透性头部创伤后出现失忆或意识丧失且格拉斯哥昏迷量表评分为15分的患者。在67例(9.4%)头部计算机断层扫描(CT)显示有急性创伤性病变的患者中,2例需要神经外科干预,1例死亡。有4个因素与CT异常结果存在统计学相关性(P < 0.05):年龄较大、白种人、颅底骨折体征以及是被机动车撞击的行人或袭击受害者。性别、顺行或逆行失忆的时长、顺背和倒背数字广度、物体回忆、一般神经检查中的局灶性异常以及主观主诉与CT异常无统计学相关性。使用逐步判别函数分析,没有单个项目或项目组合可用于将95%的患者分类到CT正常或异常组。因此,无论年龄、损伤机制或临床发现如何,对于有意识丧失或失忆的头部创伤患者,即使格拉斯哥昏迷量表评分为15分,临床上也不能完全排除颅内病变。然而,仅2例患者(0.3%)需要神经外科干预。