Revonsuo A, Portin R, Koivikko L, Rinne J O, Rinne U K
Department of Neurology, University of Turku, Finland.
Brain Cogn. 1993 Jan;21(1):87-110. doi: 10.1006/brcg.1993.1007.
In this study, we criticize the notion of bradyphrenia and argue that "slowness of thought" in Parkinson's disease (PD) must be analyzed as slowness of different information-processing stages and that unselected patients should not be used in experimental studies. We selected 32 patients with a long history of PD and 50 control subjects. Sixteen patients had mild cognitive deterioration (not dementia) and 16 patients had preserved cognitive capacities; otherwise the groups were matched. By using computerized tests, we investigated three separate stages: automatic and controlled processing and motor programming. The results indicate that patients with mild cognitive deterioration are slower than patients with preserved cognitive capacities or controls in automatic visual and in controlled processing but not in motor programming. We conclude that the slowing of controlled processing reflects the disruption of central neural networks, that a long history of PD does not necessitate cognitive slowing, and that PD is not a neuropsychologically serviceable category.
在本研究中，我们批判了思维迟缓的概念，并认为帕金森病（PD）中的“思维迟缓”必须作为不同信息处理阶段的迟缓来分析，且未经过筛选的患者不应被用于实验研究。我们选取了32例有长期PD病史的患者和50名对照受试者。16例患者有轻度认知功能减退（非痴呆），16例患者认知能力保留；除此之外，两组在其他方面相匹配。通过使用计算机化测试，我们研究了三个不同阶段：自动和控制加工以及运动编程。结果表明，在自动视觉和控制加工方面，轻度认知功能减退的患者比认知能力保留的患者或对照受试者更慢，但在运动编程方面并非如此。我们得出结论，控制加工的减慢反映了中枢神经网络的破坏，长期的PD病史并不一定会导致认知减慢，且PD在神经心理学上并非一个适用的类别。
