Lamont D W, Symonds R P, Brodie M M, Nwabineli N J, Gillis C R
West of Scotland Cancer Surveillance Unit, Greater Glasgow Health Board, Ruchill Hospital, UK.
Br J Cancer. 1993 Feb;67(2):351-7. doi: 10.1038/bjc.1993.64.
The outcome of treatment by age and socio-economic status was examined for 1,588 women with invasive cancer of cervix resident in the West of Scotland and diagnosed between 1980 and 1987. There was no difference in prognosis according to either variable once analysis was controlled for stage at presentation, treatment type and tumour grade. Tumour histology, date of treatment and health board of residence had no significant effect on survival independent of other variables. A strong correlation was found between socio-economic status and the incidence of cervical cancer in the West of Scotland. Women aged 45 and over and living in deprived areas were more likely to present with later stage tumours and to survive less well than younger patients from the more affluent parts of the region. Any additional resources which may be made available for cervical cancer screening should be directed more effectively towards those most at risk.
对居住在苏格兰西部、于1980年至1987年间确诊的1588例浸润性宫颈癌女性患者的治疗结果,按年龄和社会经济状况进行了研究。一旦对就诊时的分期、治疗类型和肿瘤分级进行分析控制,这两个变量中的任何一个对预后均无差异。肿瘤组织学、治疗日期和居住的卫生委员会,在独立于其他变量时对生存无显著影响。在苏格兰西部,社会经济状况与宫颈癌发病率之间存在很强的相关性。45岁及以上且生活在贫困地区的女性,比起该地区较富裕地区的年轻患者,更有可能出现晚期肿瘤且生存情况较差。任何可能用于宫颈癌筛查的额外资源,都应更有效地针对那些风险最高的人群。