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参加长距离雪橇比赛的犬只的血清生化变化。

Serum biochemical changes in dogs competing in a long-distance sled race.

作者信息

Hinchcliff K W, Olson J, Crusberg C, Kenyon J, Long R, Royle W, Weber W, Burr J

机构信息

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1089.

出版信息

J Am Vet Med Assoc. 1993 Feb 1;202(3):401-5.

PMID:8440630
Abstract

Fifty-five blood samples were collected from 28 dogs competing in the 1991 Yukon Quest International Sled-Dog Race to examine race-induced changes in serum biochemical values. Blood was collected after a 36-hour mandatory rest at the midpoint of the race, and again at 2 subsequent checkpoints. The mean speed of dogs between checkpoints was approximately 4.5 mph. There were no significant increases in PCV, or in serum total protein, sodium, or creatinine concentrations during the race. Mean serum potassium concentration decreased significantly (P < 0.05) from 4.8 +/- 0.4 to 4.4 +/- 0.3 to 3.9 +/- 0.3 mEq/L, as did the serum triglyceride concentration (138 +/- 52, 88 +/- 25, 81 +/- 16 mg/dl). Plasma cortisol concentration did not change significantly. Increases in the mean serum activity of creatine kinase (167, 420, 344 U/L), and aspartate aminotransferase (55, 79, 62 U/L) during the race were significant (P < 0.05). Participation in a long-distance sled race was associated with mild changes in routinely measured serum biochemical values in dogs.

摘要

从参加1991年育空探索国际雪橇犬比赛的28只犬采集了55份血样,以检测比赛引起的血清生化值变化。在比赛中点强制休息36小时后采血,随后在另外两个检查点再次采血。犬在各检查点之间的平均速度约为每小时4.5英里。比赛期间,红细胞压积、血清总蛋白、钠或肌酐浓度均无显著升高。血清钾平均浓度从4.8±0.4显著降低(P<0.05)至4.4±0.3,再降至3.9±0.3 mEq/L,血清甘油三酯浓度也如此(138±52、88±25、81±16 mg/dl)。血浆皮质醇浓度无显著变化。比赛期间肌酸激酶平均血清活性(167、420、344 U/L)和天冬氨酸氨基转移酶(55、79、62 U/L)升高显著(P<0.05)。参加长距离雪橇比赛与犬常规检测的血清生化值轻度变化有关。

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