Pehamberger H, Binder M, Steiner A, Wolff K
Department of Dermatology I, University of Vienna, Austria.
J Invest Dermatol. 1993 Mar;100(3):356S-362S. doi: 10.1111/1523-1747.ep12470285.
The majority of pigmented skin lesions can be diagnosed correctly on the basis of clinical criteria; however, there remain a surprisingly high number of small pigmented lesions in which the distinction between melanocytic and non-melanocytic and benign and malignant lesions, and thus between melanoma and non-melanoma, is difficult or impossible to make with the naked eye. Epiluminescence microscopy is a non-invasive technique that, by use of oil immersion, makes sub-surface structures of skin accessible for in vivo microscopic examination and thus provides additional criteria for the diagnosis of pigmented lesions. The technique of epiluminescence microscopy is reviewed, and the significant improvement in the clinical diagnosis of pigmented skin lesions and, in particular, melanoma by this technique is documented.
大多数色素沉着性皮肤病变可根据临床标准正确诊断；然而，仍有数量惊人的小色素沉着病变，难以或无法用肉眼区分黑素细胞性和非黑素细胞性病变、良性和恶性病变，进而区分黑色素瘤和非黑色素瘤。表皮透光显微镜检查是一种非侵入性技术，通过油浸使皮肤的皮下结构可用于体内显微镜检查，从而为色素沉着病变的诊断提供额外标准。本文综述了表皮透光显微镜检查技术，并记录了该技术在色素沉着性皮肤病变尤其是黑色素瘤临床诊断方面的显著改善。
