Yasuda M, Masai M, Shimazaki J
Department of Urology, School of Medicine, Chiba University.
Nihon Hinyokika Gakkai Zasshi. 1993 Feb;84(2):251-7. doi: 10.5980/jpnjurol1989.84.251.
Incidence of simple renal cysts was calculated in 30,316 patients receiving routine ultrasound examination in one hospital, and 170 cases visiting Chiba University Hospital were further analyzed in terms of their clinical features. Incidence of simple renal cyst was 14% in all populations and ratio of male to female was 1.6:1. Patients age ranged from 8 to 92 years (average age 58.6 years) and number of a renal cyst was increased after fifth decade in both sexes. Patients of Chiba University Hospital were examined on symptoms and clinical courses with maximal follow up to 132 months (average 18 months). Symptoms associated with simple renal cysts were: none (75.3%) pain (14.7%) and gross hematuria (6.4%). Urinalysis of patients without associated urinary diseases, showed microhematuria in 40% and proteinuria in 12%, however, grade of microhematuria and proteinuria was not correlated with size of cysts. Number of cysts tended to increase with age. Size of cysts and rate of enlargement were increasing along with age. In any cases, renal function was not and affected nor occurred malignant tumor during follow-up period. Cyst punctures with sclerosing agent were performed in 16 patients, and most of the cysts remained the same as or exceeded their original size. It is concluded that routine follow-up is sufficient in most cases without symptoms, since simple renal cysts increase slowly, and impairment of renal function and progression to malignant tumors do not occur.
在一家医院接受常规超声检查的30316名患者中计算单纯性肾囊肿的发病率,并对千叶大学医院就诊的170例患者的临床特征进行了进一步分析。所有人群中单纯性肾囊肿的发病率为14%,男女比例为1.6:1。患者年龄在8岁至92岁之间(平均年龄58.6岁),两性在50岁以后肾囊肿数量均增加。对千叶大学医院的患者进行了症状和临床病程检查,最长随访132个月(平均18个月)。与单纯性肾囊肿相关的症状有:无(75.3%)、疼痛(14.7%)和肉眼血尿(6.4%)。对无相关泌尿系统疾病的患者进行尿液分析,结果显示40%有镜下血尿,12%有蛋白尿,然而,镜下血尿和蛋白尿的程度与囊肿大小无关。囊肿数量倾向于随年龄增加。囊肿大小和增大速率随年龄增加。在任何情况下,随访期间肾功能均未受影响,也未发生恶性肿瘤。16例患者进行了囊肿穿刺硬化剂治疗,大多数囊肿保持不变或超过其原始大小。结论是,在大多数无症状的情况下,常规随访就足够了,因为单纯性肾囊肿生长缓慢,不会发生肾功能损害和进展为恶性肿瘤。