Høstmark A T, Lystad E, Vellar O D, Hovi K, Berg J E
Department of Preventive Medicine, University of Oslo, Norway.
Plant Foods Hum Nutr. 1993 Jan;43(1):55-61. doi: 10.1007/BF01088096.
The influence of a 3-week vegetarian diet and fasting on serum concentration of peroxides, lipids, apolipoproteins, and plasma fibrinogen was studied in ten middle-aged fibromyalgia/fibrositis patients (eight women, two men). Mean serum peroxide concentration (estimated as thiobarbituric acid reacting substances) was reduced from 3.60 +/- 0.14 to 2.82 +/- 0.15 umol/l (p = 0.01) and plasma fibrinogen from 3.33 +/- 0.25 to 2.74 +/- 0.15 g/l (p = 0.02). Serum total cholesterol fell from 6.61 +/- 0.50 to 4.83 +/- 0.35 mmol/l (p < 0.0001), apolipoprotein B from 1.77 +/- 0.14 to 1.31 +/- 0.11 g/l (p < 0.0001), and apolipoprotein A from 1.41 +/- 0.09 to 1.23 +/- 0.05 g/l (p = 0.03). High density lipoprotein cholesterol concentration also decreased somewhat (from 1.26 +/- 0.09 to 1.07 +/- 0.04 mmol/l, p = 0.03) An atherogenic index, reflecting the balance between low and high density lipoproteins, was reduced by 31% (from 5.74 +/- 0.79 to 3.97 +/- 0.60, p = 0.02). The results suggest that vegetarian diet/fasting may have a beneficial influence on the concentration of serum peroxides and plasma fibrinogen concentration, and on the serum level of several lipoprotein-related coronary risk factors.
在10名中年纤维肌痛/纤维织炎患者（8名女性，2名男性）中研究了为期3周的素食饮食和禁食对血清过氧化物、脂质、载脂蛋白和血浆纤维蛋白原浓度的影响。平均血清过氧化物浓度（以硫代巴比妥酸反应物质估算）从3.60±0.14降至2.82±0.15μmol/l（p = 0.01），血浆纤维蛋白原从3.33±0.25降至2.74±0.15 g/l（p = 0.02）。血清总胆固醇从6.61±0.50降至4.83±0.35 mmol/l（p < 0.0001），载脂蛋白B从1.77±0.14降至1.31±0.11 g/l（p < 0.0001），载脂蛋白A从1.41±0.09降至1.23±0.05 g/l（p = 0.03）。高密度脂蛋白胆固醇浓度也有所下降（从1.26±0.09降至1.07±0.04 mmol/l，p = 0.03）反映低密度和高密度脂蛋白之间平衡的致动脉粥样化指数降低了31%（从5.74±0.79降至3.97±0.60，p = 0.02）。结果表明，素食饮食/禁食可能对血清过氧化物浓度、血浆纤维蛋白原浓度以及几种与脂蛋白相关的冠状动脉危险因素的血清水平产生有益影响。
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