位于酿酒酵母二号染色体右臂上一段19482碱基对片段的完整序列。
The complete sequence of a 19,482 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae.
作者信息
Doignon F, Biteau N, Crouzet M, Aigle M
机构信息
Laboratoire de Biologie Moléculaire et de Séquençage, Université de Bordeaux II, France.
出版信息
Yeast. 1993 Feb;9(2):189-99. doi: 10.1002/yea.320090210.
We report here the sequence of a 19,482 bp DNA segment of chromosome II of Saccharomyces cerevisiae. The fragment contains 16 open reading frames (ORFs) covering 74% of the sequence. Four predicted products present homology with known proteins. The ORF YBR1732 exhibits a strong homology to serine hydroxymethyl transferase; the best score is 53.1% identity in 458 amino acids overlap with the serine hydroxymethyl transferase from rabbit liver. YBR1724, which shows homology with riboflavin synthase of Bacillus subtilis, is probably the RIB5 gene implied in riboflavine synthesis and mapped in this region. YBR1733 is homologous to rab protein and YBR1728 is presumably a GTPase activating protein.
我们在此报告酿酒酵母二号染色体上一段19482 bp的DNA片段序列。该片段包含16个开放阅读框（ORF），覆盖了74%的序列。四个预测产物与已知蛋白质具有同源性。开放阅读框YBR1732与丝氨酸羟甲基转移酶具有很强的同源性；在与兔肝丝氨酸羟甲基转移酶458个氨基酸的重叠区域中，最佳得分是53.1%的同一性。与枯草芽孢杆菌核黄素合酶具有同源性的YBR1724，可能是参与核黄素合成并定位在该区域的RIB5基因。YBR1733与rab蛋白同源，YBR1728可能是一种GTP酶激活蛋白。
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