Ong C N, Chia S E, Foo S C, Ong H Y, Tsakok M, Liouw P
Department of Community Medicine, National University of Singapore.
Biometals. 1993 Spring;6(1):61-6. doi: 10.1007/BF00154234.
Concentrations of lead, cadmium, methylmercury and total mercury were measured in maternal and umbilical cord blood using graphite atomic absorption spectrometry. Two essential metals, copper and zinc, were also determined using ion chromatography. Lead, copper and zinc were found to be lower in the cord blood whereas methylmercury and total mercury were higher in cord blood than in maternal blood. Little differences were noted for cadmium in maternal and cord blood. Significant positive correlations were observed between the concentrations in maternal and cord blood with regard to lead (correlation coefficient, r = 0.44), copper (r = 0.34), zinc (r = 0.29), methylmercury (r = 0.44) and total mercury (r = 0.58). These results suggest that, like essential metals, most heavy metals can move rather freely across the human placenta. The potential health effects of heavy metal transfer from mothers to young infants cannot be discounted.
采用石墨原子吸收光谱法测定了母血和脐带血中铅、镉、甲基汞和总汞的浓度。还使用离子色谱法测定了两种必需金属铜和锌的含量。结果发现，脐带血中铅、铜和锌的含量低于母血，而脐带血中甲基汞和总汞的含量高于母血。母血和脐带血中的镉含量差异不大。母血和脐带血中铅（相关系数，r = 0.44）、铜（r = 0.34）、锌（r = 0.29）、甲基汞（r = 0.44）和总汞（r = 0.58）的浓度之间存在显著的正相关。这些结果表明，与必需金属一样，大多数重金属可以相当自由地穿过人类胎盘。重金属从母亲转移到幼儿可能对健康产生的影响不容忽视。
