一名患有复发性过敏性紫癜的13岁女孩体内抗中性粒细胞胞浆自身抗体的IgG和IgA类别
IgG and IgA classes of anti-neutrophil cytoplasmic autoantibodies in a 13-year-old girl with recurrent Henoch-Schonlein purpura.
作者信息
Lin J J, Stewart C L, Kaskel F J, Fine R N
机构信息
Department of Pediatrics, State University of New York, Stony Brook 11794.
出版信息
Pediatr Nephrol. 1993 Apr;7(2):143-6. doi: 10.1007/BF00864379.
PMID:8476705
Abstract
We describe a 13-year-old girl with recurrent Henoch-Schonlein purpura whose symptoms were precipitated by upper respiratory tract infections. Her serum was positive for both IgG and IgA classes of anti-neutrophil cytoplasmic autoantibodies by immunofluorescence. The titers of both autoantibodies correlated with disease activity. The immunopathology underlying these findings is discussed.
摘要
我们描述了一名13岁复发性过敏性紫癜女孩，其症状由上呼吸道感染诱发。通过免疫荧光法检测，她的血清中IgG和IgA类抗中性粒细胞胞浆自身抗体均呈阳性。两种自身抗体的滴度均与疾病活动度相关。本文对这些发现背后的免疫病理学进行了讨论。
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