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来自硫酸盐还原古菌富铁嗜热栖热菌的甲酰基甲呋喃：四氢甲蝶呤甲酰基转移酶和N5,N10-亚甲基四氢甲蝶呤脱氢酶：与产甲烷古菌的酶的相似性

Formylmethanofuran: tetrahydromethanopterin formyltransferase and N5,N10-methylenetetrahydromethanopterin dehydrogenase from the sulfate-reducing Archaeoglobus fulgidus: similarities with the enzymes from methanogenic Archaea.

作者信息

Schwörer B, Breitung J, Klein A R, Stetter K O, Thauer R K

机构信息

Laboratorium für Mikrobiologie des Fachbereichs Biologie, Philipps-Universität Marburg, Germany.

出版信息

Arch Microbiol. 1993;159(3):225-32. doi: 10.1007/BF00248476.

DOI:10.1007/BF00248476
PMID:8481089
Abstract

The sulfate-reducing Archaeoglobus fulgidus contains a number of enzymes previously thought to be unique for methanogenic Archaea. The purification and properties of two of these enzymes, of formylmethanofuran: tetrahydromethanopterin formyltransferase and of N5,N10-methylenetetrahydromethanopterin dehydrogenase (coenzyme F420 dependent) are described here. A comparison of the N-terminal amino acid sequences and of other molecular properties with those of the respective enzymes from three methanogenic Archaea revealed a high degree of similarity.

摘要

硫酸盐还原古菌嗜热栖热袍菌含有许多以前被认为是产甲烷古菌所特有的酶。本文描述了其中两种酶，即甲酰甲呋喃：四氢甲蝶呤甲酰转移酶和N5,N10-亚甲基四氢甲蝶呤脱氢酶（依赖辅酶F420）的纯化及特性。将其N端氨基酸序列以及其他分子特性与三种产甲烷古菌各自的相应酶进行比较，结果显示出高度的相似性。

相似文献

1
Formylmethanofuran: tetrahydromethanopterin formyltransferase and N5,N10-methylenetetrahydromethanopterin dehydrogenase from the sulfate-reducing Archaeoglobus fulgidus: similarities with the enzymes from methanogenic Archaea.来自硫酸盐还原古菌富铁嗜热栖热菌的甲酰基甲呋喃：四氢甲蝶呤甲酰基转移酶和N5,N10-亚甲基四氢甲蝶呤脱氢酶：与产甲烷古菌的酶的相似性
Arch Microbiol. 1993;159(3):225-32. doi: 10.1007/BF00248476.
2
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4
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6
Function of coenzyme F420-dependent NADP reductase in methanogenic archaea containing an NADP-dependent alcohol dehydrogenase.辅酶F420依赖的NADP还原酶在含有NADP依赖型乙醇脱氢酶的产甲烷古菌中的功能
Arch Microbiol. 1997 Nov;168(5):396-402. doi: 10.1007/s002030050514.
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Salt dependence, kinetic properties and catalytic mechanism of N-formylmethanofuran:tetrahydromethanopterin formyltransferase from the extreme thermophile Methanopyrus kandleri.嗜热古菌坎氏甲烷球菌中N-甲酰基甲呋喃：四氢甲蝶呤甲酰基转移酶的盐依赖性、动力学性质及催化机制
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