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使用自体红细胞凝集技术,针对不同艾滋病病毒(HIV)流行率人群评估一种2分钟的抗HIV检测方法。

Evaluation of a 2-minute anti-human immunodeficiency virus (HIV) test using the autologous erythrocyte agglutination technique with populations differing in HIV prevalence.

作者信息

Sirivichayakul S, Phanuphak P, Tanprasert S, Thanomchat S, Uneklabh C, Phutiprawan T, Mungklavirat C, Panjurai Y

机构信息

Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

J Clin Microbiol. 1993 May;31(5):1373-5. doi: 10.1128/jcm.31.5.1373-1375.1993.

Abstract

A total of 1,800 blood specimens (1,000 from healthy blood donors, 300 from patients with sexually transmitted disease, and 500 from intravenous drug users) were simultaneously tested with anti-human immunodeficiency virus enzyme-linked immunosorbent assay (ELISA) kits and a newly developed 2-min test for anti-human immunodeficiency virus based on the principle of autologous erythrocyte agglutination (AGEN Biomedical Limited). We found that AGEN's rapid test was as sensitive and specific as the other ELISA kits.

摘要

总共1800份血液样本(1000份来自健康献血者,300份来自性传播疾病患者,500份来自静脉吸毒者)同时使用抗人类免疫缺陷病毒酶联免疫吸附测定(ELISA)试剂盒和一种基于自身红细胞凝集原理新开发的2分钟抗人类免疫缺陷病毒检测方法(AGEN生物医学有限公司)进行检测。我们发现AGEN的快速检测方法与其他ELISA试剂盒一样灵敏和特异。

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本文引用的文献

1
Autologous red cell agglutination assay for HIV-1 antibodies: simplified test with whole blood.
Science. 1988 Sep 9;241(4871):1352-4. doi: 10.1126/science.3413497.
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A rapid whole-blood immunoassay system.
Med J Aust. 1990 Jan 15;152(2):75-7. doi: 10.5694/j.1326-5377.1990.tb124459.x.
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Rapid whole blood assay for HIV-1 seropositivity using an Fab-peptide conjugate.
J Immunol Methods. 1991 Apr 8;138(1):111-9. doi: 10.1016/0022-1759(91)90070-v.

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