Mitchell E A, Taylor B J, Ford R P, Stewart A W, Becroft D M, Thompson J M, Scragg R, Hassall I B, Barry D M, Allen E M
Department of Paediatrics, School of Medicine, University of Auckland, New Zealand.
Arch Dis Child. 1993 Apr;68(4):501-4. doi: 10.1136/adc.68.4.501.
The association between dummy use and sudden infant death syndrome (SIDS) was investigated in 485 deaths due to SIDS in the postneonatal age group and compared with 1800 control infants. Parental interviews were completed in 87% of subjects. The prevalence of dummy use in New Zealand is low and varies within New Zealand. Dummy use in the two week period before death was less in cases of SIDS than in the last two weeks for controls (odds ratio (OR) 0.76, 95% confidence interval (CI) 0.57 to 1.02). Use of a dummy in the last sleep for cases of SIDS or in the nominated sleep for controls was significantly less in cases than controls (OR 0.44, 95% CI 0.26 to 0.73). The OR changed very little after controlling for a wide range of potential confounders. It is concluded that dummy use may protect against SIDS, but this observation needs to be repeated before dummies can be recommended for this purpose. If dummy sucking is protective then it is one of several factors that may explain the higher mortality from SIDS in New Zealand than in other countries, and may also explain in part the regional variation within New Zealand.
研究人员对485例新生儿后期因婴儿猝死综合征(SIDS)死亡的病例进行了调查,探讨了安抚奶嘴使用与婴儿猝死综合征之间的关联,并与1800名对照婴儿进行了比较。87%的受试者完成了家长访谈。新西兰安抚奶嘴的使用率较低,且在新西兰国内存在差异。与对照组在死亡前两周使用安抚奶嘴的情况相比,SIDS病例在死亡前两周使用安抚奶嘴的情况较少(优势比(OR)为0.76,95%置信区间(CI)为0.57至1.02)。与对照组在最后一次睡眠或指定睡眠中使用安抚奶嘴的情况相比,SIDS病例在最后一次睡眠中使用安抚奶嘴的情况显著较少(OR为0.44,95%CI为0.26至0.73)。在控制了一系列潜在混杂因素后,OR变化很小。研究得出结论,使用安抚奶嘴可能预防婴儿猝死综合征,但在推荐使用安抚奶嘴预防该疾病之前,这一观察结果需要重复验证。如果吸吮安抚奶嘴具有保护作用,那么这可能是新西兰婴儿猝死综合征死亡率高于其他国家的几个因素之一,也可能部分解释了新西兰国内的地区差异。