Mulcahy R, Hickey N, Graham I M, MacAirt J
Am Heart J. 1977 May;93(5):556-9. doi: 10.1016/s0002-8703(77)80003-3.
A total of 213 male patients who survived an initial episode of acute coronary inusfficiency or myocardial infarction for 28 days have been followed for 5 years. The effect of age, weight, severity of infarction diastolic blood pressure, serum cholesterol, and cigarette smoking at the time of the initial attack on postinfarction morbidity and death was examined. Only severity of infarction adversely influenced the long-term mortality rate; none of the factors studied was related to subsequent morbidity. The effect of subsequent cigarette smoking on morbidity and death was noted over the 5 year period. Smoking did not affect subsequent morbidity but there was an increased death rate among those who continued to smoke. This effect of smoking was independent of the severity of infarction. Improved long-term survival may be predicted for patients who stop or markedly reduce cigarette smoking.
共有213名男性患者在急性冠状动脉供血不足或心肌梗死的首次发作中存活28天,并接受了5年的随访。研究了初始发作时的年龄、体重、梗死严重程度、舒张压、血清胆固醇和吸烟对梗死后发病率和死亡率的影响。只有梗死严重程度对长期死亡率有不利影响;所研究的因素均与随后的发病率无关。在5年期间记录了随后吸烟对发病率和死亡率的影响。吸烟不影响随后的发病率,但继续吸烟的人死亡率增加。吸烟的这种影响与梗死严重程度无关。对于戒烟或显著减少吸烟的患者,可能预测其长期生存率会提高。