Hickey N, Mulcahy R, Daly L, Graham I, O'Donoghue S, Kennedy C
Br Heart J. 1983 May;49(5):423-6. doi: 10.1136/hrt.49.5.423.
Six hundred and thirty-four male patients under 60 years who survived a first attack of unstable angina or myocardial infarction were followed for a period of four years. Details of initial and follow-up smoking habits were examined. Patients who continued to smoke cigarettes or cigars had an excess mortality compared with non-smokers, with those who stopped smoking, and with cigarette smokers who changed to pipe smoking. Pipe smokers who continued smoking the pipe had an observed mortality which was greater than that of the non-smokers, but the numbers were small and the results were not statistically significant. The effect of smoking habit on mortality was not influenced by two other determinants of prognosis: age and severity of initial attack. These results confirm that the long-term prognosis of patients after unstable angina or myocardial infarction may be significantly influenced by smoking habits. They are consistent with the hypothesis that cigar and pipe smoking may have an adverse effect after myocardial infarction but further studies are needed to corroborate the association between cigar and pipe smoking and prognosis of coronary heart disease.
对634名60岁以下首次发作不稳定型心绞痛或心肌梗死且存活下来的男性患者进行了为期四年的随访。研究了他们最初及随访时的吸烟习惯细节。继续吸烟(香烟或雪茄)的患者与不吸烟者、戒烟者以及由吸香烟改为吸烟斗者相比,死亡率更高。继续吸烟斗的吸烟者观察到的死亡率高于不吸烟者,但人数较少,结果无统计学意义。吸烟习惯对死亡率的影响不受另外两个预后决定因素的影响:年龄和首次发作的严重程度。这些结果证实,不稳定型心绞痛或心肌梗死后患者的长期预后可能会受到吸烟习惯的显著影响。这与以下假设一致:心肌梗死后吸雪茄和烟斗可能产生不良影响,但需要进一步研究来证实吸雪茄和烟斗与冠心病预后之间的关联。