Kobayashi F, Takashima E, Sagawa N, Mori T, Fujii S
Department of Obstetrics and Gynecology, Kobe Central Municipal Hospital, Japan.
Arch Gynecol Obstet. 1993;252(4):185-9. doi: 10.1007/BF02426356.
Using an immunoradiometric assay, serum CA125 levels were measured in 13 women with a normal pregnancy, 9 with a spontaneous abortion, 3 with a hydatidiform mole, and 15 with a tubal pregnancy. Serum CA125 levels were high in patients with a normal pregnancy (154 +/- 169 U/ml; mean +/- S.D.), a spontaneous abortion (244 +/- 258 U/ml), or a hydatidiform mole (54 +/- 16 U/ml). In contrast, CA125 levels in patients with a tubal pregnancy (33 +/- 25 U/ml) were low, and almost all of those without uterine bleeding (25 +/- 9 U/ml) were within the normal range for non-pregnant women (< 35 U/ml). The difference between serum CA125 levels with intrauterine pregnancy and with tubal pregnancy may be ascribed to the difference of the amount of decidual tissues at the site of trophoblastic invasion.
采用免疫放射分析方法，对13例正常妊娠女性、9例自然流产女性、3例葡萄胎女性及15例输卵管妊娠女性测定血清CA125水平。正常妊娠患者（154±169 U/ml；均值±标准差）、自然流产患者（244±258 U/ml）或葡萄胎患者（54±16 U/ml）的血清CA125水平较高。相比之下，输卵管妊娠患者的CA125水平（33±25 U/ml）较低，且几乎所有无子宫出血的患者（25±9 U/ml）均在非妊娠女性的正常范围内（<35 U/ml）。宫内妊娠与输卵管妊娠血清CA125水平的差异可能归因于滋养层侵入部位蜕膜组织量的不同。
