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小于胎龄儿出生后生长情况的纵向随访

Longitudinal follow-up of growth in children born small for gestational age.

作者信息

Albertsson-Wikland K, Wennergren G, Wennergren M, Vilbergsson G, Rosberg S

机构信息

Department of Paediatrics I, University of Göteborg, Sweden.

出版信息

Acta Paediatr. 1993 May;82(5):438-43. doi: 10.1111/j.1651-2227.1993.tb12718.x.

DOI:10.1111/j.1651-2227.1993.tb12718.x
PMID:8518519
Abstract

Postnatal growth was followed in a population-based group of 123 small-for-gestational-age (SGA, birth weight < -2 SD) children (66 boys and 57 girls) to four years of age in order to determine the incidence and time of catch-up growth. Gestational age was determined by ultrasound in gestational weeks 16-17 in all pregnancies, thus eliminating the problem of distinguishing between SGA and preterm infants. Infants with well-defined causes for slow growth rate, i.e. those infants with chromosomal disorders, severe malformations, intrauterine viral infections or cerebral palsy, were excluded. The boys showed an extremely fast weight catch-up, 85% of them reaching weights greater than -2 SD at the age of three months and remaining above this level to the end of the study period. Such a fast catch-up growth was observed in only two-thirds of the girls, but at four years of age 85% of the girls were also above -2 SD. Length catch-up was more gradual than weight catch-up. Of the boys, 54% had lengths below -2 SD at birth, 26% at 1 year of age, 22% at 2 years of age, 17% at 2.5 years of age and 11% (n = 8) at 4 years of age. Corresponding figures for girls were: 69% at birth, 28% at 1 year, 15% at 2 years, 12% at 2.5 years and 5% (n = 3) at 4 years. At 4 years of age, only six boys and three girls remained below -2 SD for both weight and height.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对一组基于人群的123名小于胎龄儿(SGA,出生体重<-2标准差)儿童(66名男孩和57名女孩)进行出生后生长情况跟踪,直至4岁,以确定追赶生长的发生率和时间。所有妊娠在孕16 - 17周时通过超声确定孕周,从而消除了区分SGA和早产儿的问题。排除生长速率缓慢原因明确的婴儿,即患有染色体疾病、严重畸形、宫内病毒感染或脑瘫的婴儿。男孩体重追赶极快,85%的男孩在3个月大时体重超过-2标准差,并在研究期末保持在该水平以上。只有三分之二的女孩出现如此快速的追赶生长,但在4岁时,85%的女孩体重也超过了-2标准差。身长追赶比体重追赶更缓慢。男孩中,出生时54%的身长低于-2标准差,1岁时为26%,2岁时为22%,2.5岁时为17%,4岁时为11%(n = 8)。女孩的相应数据为:出生时69%,1岁时28%,2岁时15%,2.5岁时12%,4岁时5%(n = 3)。4岁时,只有6名男孩和3名女孩体重和身高均低于-2标准差。(摘要截选至250词)

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