Holmes A R, Cannon R D, Jenkinson H F
Department of Oral Biology and Oral Pathology, University of Otago, Dunedin, New Zealand.
J Ind Microbiol. 1995 Sep;15(3):208-13. doi: 10.1007/BF01569827.
The yeast Candida albicans coaggregates with a variety of streptococcal species, an interaction that may promote oral colonization by yeast cells. C. albicans and Candida tropicalis are the yeasts most frequently isolated from the human oral cavity and our data demonstrate that both these species bind to Streptococcus gordonii NCTC 7869 while two other Candida species (Candida krusei and Candida kefyr) do not. Adherence of C. albicans was greatest when the yeast had been grown at 30 degrees C to mid-exponential growth phase. For 21 strains of C. albicans there was a positive correlation between the ability to adhere to S. gordonii and adherence to experimental salivary pellicle. Whole saliva either stimulated or slightly inhibited adherence of C. albicans to S. gordonii depending on the streptococcal growth conditions. The results suggest that the major salivary adhesins and coaggregation adhesins of C. albicans are co-expressed.
白色念珠菌能与多种链球菌形成共聚体，这种相互作用可能会促进酵母细胞在口腔中的定植。白色念珠菌和热带念珠菌是最常从人类口腔中分离出的酵母，我们的数据表明这两种念珠菌都能与戈登链球菌NCTC 7869结合，而其他两种念珠菌（克鲁斯念珠菌和凯弗念珠菌）则不能。当白色念珠菌在30℃培养至指数生长中期时，其黏附能力最强。对于21株白色念珠菌，其黏附戈登链球菌的能力与黏附实验性唾液薄膜的能力之间呈正相关。全唾液对白色念珠菌黏附戈登链球菌的作用取决于链球菌的生长条件，要么刺激其黏附，要么轻微抑制其黏附。结果表明，白色念珠菌的主要唾液黏附素和共聚黏附素是共同表达的。
