Haley C S
Roslin Institute, Edinburgh, Midlothian, UK.
Trends Genet. 1995 Dec;11(12):488-92. doi: 10.1016/s0168-9525(00)89158-1.
Markers have been used for some time to study the genetic control of economically important traits in livestock. The early work was based on single loci and detected some significant effects, but results were often inconsistent across studies. Now that complete microsatellite-based maps of the major species are becoming available, more complete and rigorous scans of the genome are possible. The first of these have detected some surprisingly large effects, both within breeds and in breed crosses. As research workers digest these results and their implications for livestock breeding programmes and ponder further research, commercial breeding companies have already started applying the first fruits of marker research to breed a better animal.
标记物已被用于研究家畜经济重要性状的遗传控制有一段时间了。早期的工作基于单一位点，检测到了一些显著效应，但研究结果在不同研究中往往不一致。如今，主要物种基于微卫星的完整图谱已可获取，对基因组进行更完整、更严谨的扫描成为可能。其中首批扫描已检测到一些惊人的大效应，无论是在品种内还是品种杂交中。当研究人员消化这些结果及其对家畜育种计划的影响并思考进一步研究时，商业育种公司已经开始应用标记物研究的首批成果来培育更优良的动物。
