Ashby K, Lo S K
Division of Gastroenterology, Harbor-UCLA Medical Center, UCLA School of Medicine, Torrance 90502, USA.
Gastrointest Endosc. 1995 Oct;42(4):306-11. doi: 10.1016/s0016-5107(95)70127-3.
Pancreatic ductal strictures may lead to pancreatitis, with associated pain and nausea. Very little literature is available regarding stent placement for this problem; the efficacy of stenting, expected stent viability, and safety of the procedure require further study. In this series, 21 patients with pancreatic ductal strictures underwent a total of 42 ERCPs with pancreatic stent placement. Eighty-six percent of patients experienced significant improvement in their symptom score after at least 1 session; however, relief was usually not evident until day 7. Stent viability averaged 26.9 days, but it was significantly longer for patients with pancreatic cancer. Overall, pancreatic ductal stenting can relieve symptoms of pain and nausea, but relief is usually short-lived. It may be useful only for short-term therapeutic trials and to provide temporary relief in highly selected cases.
胰腺导管狭窄可能导致胰腺炎,并伴有疼痛和恶心。关于针对该问题进行支架置入的文献非常少;支架置入的疗效、预期的支架存活时间以及该操作的安全性都需要进一步研究。在本系列研究中,21例胰腺导管狭窄患者共接受了42次经内镜逆行胰胆管造影术(ERCP)并置入胰腺支架。86%的患者在至少1次治疗后症状评分有显著改善;然而,通常直到第7天才明显缓解。支架平均存活时间为26.9天,但胰腺癌患者的存活时间明显更长。总体而言,胰腺导管支架置入可缓解疼痛和恶心症状,但缓解通常是短暂的。它可能仅适用于短期治疗试验以及为高度选择的病例提供临时缓解。