Chadduck W M, Duong D H, Kast J M, Donahue D J
Department of Neurosurgery, Children's National Medical Center, Washington, DC 20010, USA.
Childs Nerv Syst. 1995 Oct;11(10):579-83. doi: 10.1007/BF00300996.
Cerebellar hemorrhage is a devastating condition with morbidity and mortality related not only to the etiology of the hemorrhage, but also to the timing of the intervention. Sixteen consecutive pediatric patients with acute cerebellar hemorrhages are presented: 6 had vascular abnormalities, 3 had tumors, and 2 had hemorrhages of unknown etiology. Thirteen of the 16 patients survived with only 1 of the 13 having persistent vegetative state as a neurologic outcome. Six of 8 patients presenting in a moribund condition had good outcomes, and 3 of 4 patients presenting with fixed and dilated pupils also had good outcomes. Thus, in contrast to adults, rapid evaluation by CT scanning, followed by the judicious use of ventricular drainage and prompt surgical treatment, have resulted in favorable outcomes in pediatric patients despite their poor clinical presentations. None of the neonates having cerebellar hemorrhages required surgical intervention; their courses could be followed clinically and with transfontanel ultrasound.
小脑出血是一种严重的疾病,其发病率和死亡率不仅与出血病因有关,还与干预时机有关。本文报告了16例连续性急性小脑出血的儿科患者:6例有血管异常,3例有肿瘤,2例出血病因不明。16例患者中有13例存活,其中13例中只有1例出现持续性植物状态这一神经学转归。8例濒死状态就诊的患者中有6例预后良好,4例出现瞳孔固定散大的患者中有3例预后也良好。因此,与成人不同,尽管儿科患者临床表现不佳,但通过CT扫描快速评估,随后谨慎使用脑室引流并及时进行手术治疗,已使他们获得了良好的预后。所有小脑出血的新生儿均无需手术干预;可通过临床观察和经囟门超声对其病程进行跟踪。