MacKenzie W R, Kazmierczak J J, Davis J P
CDC, EPO, DFE, MS C-08, Atlanta, GA 30333, USA.
Epidemiol Infect. 1995 Dec;115(3):545-53. doi: 10.1017/s0950268800058714.
An outbreak of cyptosporidiosis occurred in late April 1993 among resort hotel guests which was temporally associated with, but geographically distant from, a massive waterborne outbreak of cryptosporidiosis in Milwaukee, Wisconsin, that occurred in late March and early April of 1993. A case-control study was performed among groups with members who reported illness and among a systemic sample of groups who stayed at the resort hotel during the risk period. Of 120 persons interviewed, 51 (43%) met the case definition. Swimming in the resort hotel's pool was significantly associated with case status (OR = 9.8; 95% Cl 3.4, 29.7), as was consumption of ice from the hotel's ice machines (OR = 2.3; 95% Cl 1.01, 5.2). When analysis was restricted only to laboratory-confirmed cases and controls, swimming pool use was the only risk factor significantly associated with illness (OR = 13.0; 95% Cl 2.6, 88.7). Following waterborne outbreaks of cryptosporidiosis associated with water supplies, swimming pools should be considered as possible ongoing sources for transmission regionally.
1993年4月下旬,一家度假酒店的客人中爆发了隐孢子虫病,这在时间上与1993年3月下旬和4月初发生在威斯康星州密尔沃基的大规模水源性隐孢子虫病爆发有关,但在地理上相距甚远。在报告患病的群体成员以及在风险期入住该度假酒店的群体的系统样本中进行了病例对照研究。在接受访谈的120人中,51人(43%)符合病例定义。在度假酒店游泳池游泳与病例状态显著相关(比值比=9.8;95%可信区间3.4,29.7),从酒店制冰机取用冰块也与之相关(比值比=2.3;95%可信区间1.01,5.2)。当分析仅限于实验室确诊的病例和对照时,使用游泳池是与疾病显著相关的唯一危险因素(比值比=13.0;可信区间95%2.6,88.7)。在与供水相关的水源性隐孢子虫病爆发之后,游泳池应被视为区域内可能持续存在的传播源。