Gupta R, Prakash H, Majumdar S, Sharma S, Gupta V P
Department of Medicine, Monilek Hospital and Research Centre, Jaipur, India.
Indian Heart J. 1995 Jul-Aug;47(4):331-8.
To determine the prevalence of coronary heart disease (CHD) and coronary risk factors in an urban Indian population, we studied a random sample of population of Jaipur. A physician-administered questionnaire, physical examination and a 12-lead electrocardiogram was performed on 2,212 adults of > or = 20 years of age (males 1,415, females 797). CHD was diagnosed on the basis of past documentation, response to WHO-Rose questionnaire or changes in the electrocardiogram. The overall prevalence of CHD was 7.6 percent (168 cases). The prevalence rate was 6.0 percent (84) in males and 10.4 percent (84) in females with an age-related increase in prevalence ('p' for trend < 0.001). When diagnosed on the basis of electrocardiographic changes alone (Q, ST or T wave), the prevalence was 5.2 percent (116), with 3.5 percent in males and 8.4 percent in females. CHD was silent in 57 percent males and 79 percent females. Coronary risk factors were observed in a significant proportion: smoking in 32 percent (males 39 percent, females 19 percent), hypertension (> or = 140/90 mm Hg) in 31 percent (males 30 percent, females 34 percent-JNC-V) and > or = 160/95 mm Hg in 11 percent (males 10 percent, females 12 percent; WHO classification), diabetes in 1 percent and sedentary habits in 71 percent. Additional risk factors were generalised obesity (body-mass index > or = 27 Kg/m2) in 11 percent and truncal obesity (waist-hip ratio > 0.95) in 17 percent males and 13 percent females. Significant association of CHD prevalence were seen with age, sedentary habits and presence of hypertension in both males and females, and in addition with smoking in males.
为了确定印度城市人口中冠心病(CHD)的患病率及相关危险因素,我们对斋浦尔的人群进行了随机抽样研究。对2212名年龄大于或等于20岁的成年人(男性1415名,女性797名)进行了由医生填写的问卷调查、体格检查及12导联心电图检查。冠心病根据既往病历记录、对世界卫生组织-罗斯问卷的回答或心电图变化来诊断。冠心病的总体患病率为7.6%(168例)。男性患病率为6.0%(84例),女性为10.4%(84例),患病率随年龄增长而增加(趋势检验“p”值<0.001)。仅根据心电图变化(Q波、ST段或T波)诊断时,患病率为5.2%(116例),男性为3.5%,女性为8.4%。57%的男性和79%的女性冠心病无症状。相当比例的人存在冠心病危险因素:32%的人吸烟(男性39%,女性19%),31%的人患有高血压(收缩压大于或等于140/90 mmHg,男性30%,女性34%——美国国家联合委员会第5版标准),11%的人收缩压大于或等于160/95 mmHg(男性10%,女性12%;世界卫生组织分类标准),1%的人患有糖尿病,71%的人有久坐习惯。另外的危险因素包括11%的人全身肥胖(体重指数大于或等于27 Kg/m2),17%的男性和13%的女性有腹型肥胖(腰臀比>0.95)。在男性和女性中,冠心病患病率与年龄、久坐习惯和高血压显著相关,此外男性还与吸烟有关。