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亚裔印度人:对美国这一研究不足群体的冠状动脉疾病综述。

Asian-Indians: a review of coronary artery disease in this understudied cohort in the United States.

作者信息

Ardeshna Devarshi R, Bob-Manuel Tamunoinemi, Nanda Amit, Sharma Arindam, Skelton William Paul, Skelton Michelle, Khouzam Rami N

机构信息

College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

出版信息

Ann Transl Med. 2018 Jan;6(1):12. doi: 10.21037/atm.2017.10.18.

Abstract

Coronary artery disease (CAD) is a major cause of cardiovascular death worldwide. Prevalence of CAD is highly variable among different races. Asian Indians have been noted to have the highest CAD rates and the conventional risk factors fail to explain this difference completely. Asian Indians constitute a fifth of the global population, and the higher rates of CAD in this population constitute a major health challenge. There have been studies in the early 2000s that investigate the risk factors in this population; however, very few studies have been done since then that explore the higher CAD rates in Asian Indians. This is a comprehensive and current review of the known risk factors for CAD in Asian Indians and strategies physicians should consider relieving this burden.

摘要

冠状动脉疾病(CAD)是全球心血管死亡的主要原因。CAD的患病率在不同种族之间差异很大。亚洲印度人被认为CAD发病率最高,而传统的风险因素并不能完全解释这种差异。亚洲印度人占全球人口的五分之一,该人群中较高的CAD发病率构成了一项重大的健康挑战。在21世纪初有研究调查了该人群的风险因素;然而,从那时起,很少有研究探讨亚洲印度人CAD发病率较高的原因。这是一篇关于亚洲印度人CAD已知风险因素的全面且最新的综述,以及医生应考虑减轻这一负担的策略。

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本文引用的文献

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Genetics of Coronary Artery Disease.冠状动脉疾病的遗传学。
Circ Res. 2016 Feb 19;118(4):564-78. doi: 10.1161/CIRCRESAHA.115.306566.
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Sex differences in coronary artery disease: pathological observations.冠状动脉疾病的性别差异:病理学观察。
Atherosclerosis. 2015 Mar;239(1):260-7. doi: 10.1016/j.atherosclerosis.2015.01.017. Epub 2015 Jan 20.
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Coronary heart disease in Indian Asians.印度裔亚洲人的冠心病
Glob Cardiol Sci Pract. 2014 Jan 29;2014(1):13-23. doi: 10.5339/gcsp.2014.4. eCollection 2014.
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