Vall Mayans M, Casabona J, Rabella N, De Miniac D
AIDS Programme, Department of Health, Generalitat de Catalunya, Barcelona, Spain.
Eur J Clin Microbiol Infect Dis. 1995 Aug;14(8):710-3. doi: 10.1007/BF01690881.
Paired samples of saliva and serum from 286 high-risk subjects were tested for HIV using two commercial enzyme immunoassays following the same WHO testing strategy supplemented with a Western blot technique. Agreement between HIV testing in both sample types was 98.9% (95% confidence interval: 97.7-100). The sensitivity of an EIA (Wellcozyme GACELISA) alone for saliva was 100% (133/133) and the specificity 98.7% (151/153). These results support previous data showing that in some situations saliva might be an effective alternative to serum for HIV testing.
按照世界卫生组织相同的检测策略并辅以蛋白质印迹技术，使用两种商用酶免疫测定法对286名高危受试者的配对唾液和血清样本进行了HIV检测。两种样本类型的HIV检测结果一致性为98.9%（95%置信区间：97.7 - 100）。单独使用酶免疫测定法（Wellcozyme GACELISA）检测唾液时，灵敏度为100%（133/133），特异性为98.7%（151/153）。这些结果支持了先前的数据，表明在某些情况下，唾液可能是HIV检测中血清的有效替代物。
