加拿大萨斯喀彻温省对青霉素敏感性降低的脑膜炎奈瑟菌。
Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, Canada.
作者信息
Blondeau J M, Ashton F E, Isaacson M, Yaschuck Y, Anderson C, Ducasse G
机构信息
Department of Clinical Microbiology, St. Paul's Hospital, Saskatoon, Ottawa, Canada.
出版信息
J Clin Microbiol. 1995 Jul;33(7):1784-6. doi: 10.1128/jcm.33.7.1784-1786.1995.
Abstract
Moderately penicillin-resistant Neisseria meningitidis is rare in North America. We report an outbreak of meningococcal disease in Saskatoon, Saskatchewan, Canada, with serogroup C N. meningitidis. The MICs of penicillin ranged from 0.12 to 0.25 micrograms/ml, and all isolates showing decreased susceptibility had identical genomic fingerprints when they were compared by pulsed-field gel electrophoresis. Our data indicate that N. meningitidis that is moderately resistant to penicillin is prevalent in Saskatchewan, Canada.
摘要
中度耐青霉素的脑膜炎奈瑟菌在北美较为罕见。我们报告了加拿大萨斯喀彻温省萨斯卡通市一起由C群脑膜炎奈瑟菌引起的脑膜炎球菌病暴发。青霉素的最低抑菌浓度范围为0.12至0.25微克/毫升，通过脉冲场凝胶电泳比较时，所有显示敏感性降低的分离株具有相同的基因组指纹图谱。我们的数据表明，中度耐青霉素的脑膜炎奈瑟菌在加拿大萨斯喀彻温省很普遍。
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