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使用猫腹水或鼠单克隆抗体在石蜡包埋组织中对猫传染性腹膜炎病毒抗原进行免疫组织学检测。

Immunohistological demonstration of feline infectious peritonitis virus antigen in paraffin-embedded tissues using feline ascites or murine monoclonal antibodies.

作者信息

Tammer R, Evensen O, Lutz H, Reinacher M

机构信息

Inst. Vet.-Univ, Giessen, Germany.

出版信息

Vet Immunol Immunopathol. 1995 Nov;49(1-2):177-82. doi: 10.1016/0165-2427(95)05459-j.

DOI:10.1016/0165-2427(95)05459-j
PMID:8588340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7119862/
Abstract

Feline infectious peritonitis (FIP) virus antigen was demonstrated after methanol, ethanol or formalin fixation in paraffin-embedded tissues by means of monoclonal and polyclonal antibodies. The monoclonal antibody was induced by immunization with transmissible gastroenteritis virus. Polyclonal antibodies were obtained by purification on protein A-Sepharose of ascites fluid from a cat with FIP. Almost all cats diagnosed as suffering from FIP by postmortem and histological examination exhibited FIP virus (FIPV) antigen in macrophages in granulomas whereas FIPV antigen was only once demonstrable in another location.

摘要

通过单克隆抗体和多克隆抗体，在甲醇、乙醇或福尔马林固定的石蜡包埋组织中证实了猫传染性腹膜炎（FIP）病毒抗原。单克隆抗体是通过用传染性胃肠炎病毒免疫诱导产生的。多克隆抗体是通过对一只患有FIP的猫的腹水进行蛋白A-琼脂糖纯化获得的。几乎所有经尸检和组织学检查诊断为患有FIP的猫，在肉芽肿中的巨噬细胞中都显示出FIP病毒（FIPV）抗原，而FIPV抗原仅在另一个位置被证实过一次。

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本文引用的文献

1
An immunohistochemical study on the cytogenetic origin of pulmonary multinucleate giant cells in porcine dermatosis vegetans.
Vet Pathol. 1993 Mar;30(2):162-70. doi: 10.1177/030098589303000209.
2
The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.注入的辣根过氧化物酶在小鼠肾近端小管吸收的早期阶段：一种新技术的超微结构细胞化学研究
J Histochem Cytochem. 1966 Apr;14(4):291-302. doi: 10.1177/14.4.291.
3
Peroxidase-labeled antibody. A new method of conjugation.过氧化物酶标记抗体。一种新的偶联方法。
J Histochem Cytochem. 1974 Dec;22(12):1084-91. doi: 10.1177/22.12.1084.
4
Specificity assessment of feline T-lymphotropic lentivirus serology.
Zentralbl Veterinarmed B. 1988 Dec;35(10):773-8. doi: 10.1111/j.1439-0450.1988.tb00559.x.
5
Demonstration of feline infectious peritonitis virus in conjunctival epithelial cells from cats. A simple and reliable method for clinical veterinary virology screening.猫传染性腹膜炎病毒在猫结膜上皮细胞中的检测。一种用于临床兽医病毒学筛查的简单可靠方法。
APMIS. 1989 Sep;97(9):820-4. doi: 10.1111/j.1699-0463.1989.tb00483.x.
6
[A modification of the ABC method (avidin-biotin-peroxidase complex) for the detection of viral antigens in coronavirus infections in cats (FIP) and parvovirus type 2 infections in dogs].[一种用于检测猫冠状病毒感染（猫传染性腹膜炎）和犬细小病毒2型感染中病毒抗原的ABC法（抗生物素蛋白-生物素-过氧化物酶复合物）改良方法]
Zentralbl Veterinarmed B. 1989 Jul;36(5):321-32.
7
A comparison between immunofluorescence staining on smears from Membrana nictitans (M3 test), immunohistopathology and routine pathology in cats with suspected feline infectious peritonitis (FIP).对疑似猫传染性腹膜炎（FIP）的猫，比较瞬膜涂片免疫荧光染色（M3试验）、免疫组织病理学和常规病理学检查结果。
Acta Vet Scand. 1991;32(2):171-6. doi: 10.1186/BF03546977.
8
Perspectives on the epizootiology of feline enteric coronavirus and the pathogenesis of feline infectious peritonitis.猫肠道冠状病毒的流行病学及猫传染性腹膜炎的发病机制研究进展
Vet Microbiol. 1991 Aug 15;28(3):243-55. doi: 10.1016/0378-1135(91)90079-u.
9
Immunohistological demonstration of pyruvate kinase isoenzyme type L in rat with monoclonal antibodies.用单克隆抗体对大鼠丙酮酸激酶L型同工酶进行免疫组织学鉴定。
J Histochem Cytochem. 1992 May;40(5):665-73. doi: 10.1177/40.5.1374093.
10
Feline coronavirus antibodies in cats.猫体内的猫冠状病毒抗体。
Vet Rec. 1992 Aug 29;131(9):202-3. doi: 10.1136/vr.131.9.202-a.