Faber T
Dept. of Anaesthesiology and Intensive Care, Bispebjerg University Hospital, Copenhagen, Denmark.
Acta Anaesthesiol Scand Suppl. 1995;107:33-6. doi: 10.1111/j.1399-6576.1995.tb04327.x.
Mixed venous oxygen content (commonly measured as oxygen saturation) is a highly relevant parameter in the monitoring of critically ill patients; unfortunately, its measurement requires catheterization of the pulmonary artery. Though less invasive, the central venous oxygen saturation is an unsatisfactory substitute, due to fluctuations in perfusion distribution and regional oxygen extraction in the course of illness. The present study examined the relation of oxygen contents in simultaneously withdrawn central venous and mixed venous blood samples from critically ill patients, in order to validate a hypothetical algorithm for the estimation of mixed venous oxygen content from a central venous sample: Although the proposed algorithm had a fairly high power of prediction, its merits in comparison to assuming simple proportionality between central venous and mixed venous oxygen content seemed marginal. However, as it is likely that the results so far are mathematically coupled, further prospective studies are necessary.
混合静脉血氧含量（通常以血氧饱和度衡量）是危重症患者监测中一个高度相关的参数；不幸的是，其测量需要进行肺动脉插管。中心静脉血氧饱和度虽然侵入性较小，但由于疾病过程中灌注分布和局部氧摄取的波动，它是一个不尽人意的替代指标。本研究检测了危重症患者同时采集的中心静脉血和混合静脉血样本中氧含量的关系，以验证一种从中心静脉样本估算混合静脉血氧含量的假设算法：尽管所提出的算法具有相当高的预测能力，但与假设中心静脉和混合静脉血氧含量之间存在简单比例关系相比，其优势似乎微不足道。然而，由于目前的结果可能在数学上相互关联，因此有必要进行进一步的前瞻性研究。
