Heiselman D, Jones J, Cannon L
J Clin Monit. 1986 Oct;2(4):237-45. doi: 10.1007/BF02851172.
Fiberoptic pulmonary artery catheters provide a practical method for continuously measuring the amount of oxygen in mixed venous blood. To characterize the usefulness of mixed venous oxygen saturation in managing patients with sepsis, we performed serial hemodynamic measurements on 20 patients with documented septic shock. There was a highly significant positive correlation between increases or decreases of 5% or more in mixed venous oxygen saturation and corresponding changes in oxygen delivery (r = 0.95) and oxygen consumption (r = 0.96). Mixed venous oxygen saturation less than 65% was clinically unacceptable in patients with sepsis and was associated with a poor prognosis. In this study, measurement of mixed venous oxygen saturation was a valuable predictor of survival in patients with septic shock and provided a means of continuously monitoring the status of tissue oxygenation.
纤维光学肺动脉导管提供了一种连续测量混合静脉血中氧含量的实用方法。为了描述混合静脉血氧饱和度在脓毒症患者管理中的有用性，我们对20例确诊为感染性休克的患者进行了系列血流动力学测量。混合静脉血氧饱和度升高或降低5%或更多与氧输送（r = 0.95）和氧消耗（r = 0.96）的相应变化之间存在高度显著的正相关。脓毒症患者中，混合静脉血氧饱和度低于65%在临床上是不可接受的，且与预后不良相关。在本研究中，混合静脉血氧饱和度的测量是感染性休克患者生存的有价值预测指标，并提供了一种连续监测组织氧合状态的方法。
