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连续胸段硬膜外输注用于漏斗胸畸形修复术后镇痛。

Continuous thoracic epidural infusions for postoperative analgesia after pectus deformity repair.

作者信息

McBride W J, Dicker R, Abajian J C, Vane D W

机构信息

Division of Pediatric Surgery, University of Vermont College of Medicine, Burlington 05405, USA.

出版信息

J Pediatr Surg. 1996 Jan;31(1):105-7; discussion 107-8. doi: 10.1016/s0022-3468(96)90329-2.

Abstract

PURPOSE

To determine whether continuous epidural analgesia after repair of a pectus deformity is a viable and safe alternative to high-dose narcotics in children.

METHODS

Data were collected prospectively for 19 children (4 to 17 years of age; 15 boys, 4 girls) who underwent pectus excavatum (14) or carinatum (5) repair between June 1, 1991 and July 1, 1994. Seventeen had a thoracic epidural catheter placed for postoperative pain control and two did not. The epidural catheter was routinely plead preoperatively by the anesthesiologist at the T3-T8 level, after induction of general anesthesia. Epidural catheters were test-dosed with local anesthesia alone or in combination with fentanyl, and afterward a continuous epidural infusion was maintained on the floor. Postoperative pain was assessed by nursing and house staff on the Wong-Baker scale, with adjustment of the dose rate or analgesic medication as appropriate.

RESULTS

All patients had extubation before leaving the operating room and were sent to the general pediatrics ward after leaving the recovery room. The average duration of the epidural was 69 hours (range, 20 to 116 hours). Sixteen patients received their test epidural dose preoperatively, and one patient had his in the recovery room. Fifteen epidural initially were dosed with bupivicaine (1 to 2 mg/kg) alone or in combination with fentanyl (1 to 2 micrograms/kg). Two patients received initial doses of lidocaine (1 to 1.5 micrograms/kg). Ten of 17 patients received fentanyl (1 microgram/kg/h) with bupivicaine (0.5 to 1.0 mg/kg/h) in the epidural as their maintenance medication, and the remainder received bupivicaine alone at the same dosage rate. Eight of 17 patients required additional intermittent supplemental narcotics, with an average of two doses of intravenous morphine per day (0.1 mg/kg) over the first 3 postoperative days. In contrast, the two patients who did not have an epidural catheter for pain control required high-dose intravenous morphine (0.2 mg/kg) every 2 to 3 hours for the first 3 to 4 postoperative days. No catheter-related complications occurred.

CONCLUSION

Thoracic epidural analgesia was completely successful in nine (53%) children who underwent repair of pectus deformity, and effectively reduced the intravenous narcotic demand in the other eight. Pain control was excellent, and no catheter-related complications were encountered. The data show that this method of analgesia in children is a safe and attractive alternative to intravenous narcotics, and eliminates the potential disadvantages of sedation and respiratory compromise.

摘要

目的

确定小儿漏斗胸或鸡胸畸形修复术后持续硬膜外镇痛是否是一种可行且安全的替代大剂量麻醉药的方法。

方法

前瞻性收集1991年6月1日至1994年7月1日期间接受漏斗胸修复术(14例)或鸡胸修复术(5例)的19名儿童(4至17岁;15名男孩,4名女孩)的数据。17例放置了胸段硬膜外导管用于术后疼痛控制,2例未放置。硬膜外导管由麻醉医生在全身麻醉诱导后常规于术前放置在T3 - T8水平。硬膜外导管单独或联合芬太尼进行试验剂量注射,之后在病房维持持续硬膜外输注。术后疼痛由护理人员和住院医生根据面部表情疼痛评分量表进行评估,并酌情调整剂量率或镇痛药物。

结果

所有患者在离开手术室前均已拔管,离开恢复室后被送往普通儿科病房。硬膜外镇痛的平均持续时间为69小时(范围20至116小时)。16例患者术前接受了试验剂量的硬膜外注射,1例在恢复室接受。15例硬膜外最初单独给予布比卡因(1至2mg/kg)或联合芬太尼(1至2μg/kg)。2例患者最初接受利多卡因(1至1.5μg/kg)。17例患者中有10例在硬膜外给予芬太尼(1μg/kg/h)联合布比卡因(0.5至1.0mg/kg/h)作为维持用药,其余患者以相同剂量率单独接受布比卡因。17例患者中有8例需要额外的间歇性补充麻醉药,术后前3天平均每天静脉注射吗啡2剂(0.1mg/kg)。相比之下,2例未放置硬膜外导管进行疼痛控制的患者在术后前3至4天每2至3小时需要高剂量静脉注射吗啡(0.2mg/kg)。未发生与导管相关的并发症。

结论

9例(53%)接受漏斗胸或鸡胸畸形修复术的儿童胸段硬膜外镇痛完全成功,另外8例有效减少了静脉麻醉药的需求。疼痛控制良好,未遇到与导管相关的并发症。数据表明,这种小儿镇痛方法是静脉麻醉药的一种安全且有吸引力的替代方法,消除了镇静和呼吸功能受损的潜在弊端。

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