Simonetti O P, Finn J P, White R D, Laub G, Henry D A
MR Research and Development, Siemens Medical Systems, Iselin, NJ 08830, USA.
Radiology. 1996 Apr;199(1):49-57. doi: 10.1148/radiology.199.1.8633172.
To develop a short-inversion-time inversion-recovery (STIR) magnetic resonance imaging pulse sequence for evaluating the myocardium that is relatively free of flow and motion artifact.
The authors implemented a breath-hold, cardiac-triggered STIR sequence with preparatory radio-frequency pulses to eliminate signal from flowing blood. A segmented rapid acquisition with relaxation enhancement (turbo spin echo) readout was used, with the inversion-recovery delay adjusted to null fat. The sequence was implemented at 1.0 and 1.5 T and tested in phantoms, five healthy volunteers, and three patients.
Phantom studies confirmed the expected behavior of the sequence. In the volunteers, fat-suppressed images of the heart with STIR contrast were generated in a breath-hold period. Blood in the heart chambers was uniformly nulled, and motion artifacts were effectively suppressed. Focal high signal intensity consistent with edema was seen in two patients with acute myocardial infarction; in a third patient, a paracardiac mass was visualized and sharply demarcated relative to normal myocardium.
Fast STIR imaging of the heart with effective suppression of flow and motion artifacts was implemented. The approach has much potential for high-contrast imaging in a variety of diseases affecting the heart and mediastinum.
开发一种短反转时间反转恢复(STIR)磁共振成像脉冲序列,用于评估相对无血流和运动伪影的心肌。
作者实施了一种屏气、心脏触发的STIR序列,采用预备性射频脉冲消除血流信号。采用分段快速采集弛豫增强(涡轮自旋回波)读出,将反转恢复延迟调整为使脂肪信号为零。该序列在1.0和1.5 T场强下实施,并在体模、5名健康志愿者和3名患者中进行测试。
体模研究证实了该序列的预期表现。在志愿者中,在屏气期间生成了具有STIR对比的心脏脂肪抑制图像。心腔内血液信号均匀被抑制,运动伪影得到有效抑制。在两名急性心肌梗死患者中可见与水肿一致的局灶性高信号强度;在第三名患者中,可见心旁肿块,相对于正常心肌有清晰的边界。
实现了对心脏的快速STIR成像,有效抑制了血流和运动伪影。该方法在对影响心脏和纵隔的各种疾病进行高对比度成像方面具有很大潜力。