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维多利亚州食管癌和近端胃癌的发病率趋势

Incidence trends in oesophageal and proximal gastric carcinoma in Victoria.

作者信息

Thomas R J, Lade S, Giles G G, Thursfield V

机构信息

Department of Surgery, Western Hospital, Footscray, Australia.

出版信息

Aust N Z J Surg. 1996 May;66(5):271-5. doi: 10.1111/j.1445-2197.1996.tb01183.x.

DOI:10.1111/j.1445-2197.1996.tb01183.x
PMID:8634040
Abstract

BACKGROUND

There is clinical evidence that adenocarcinoma of the lower oesophagus is increasing in the Australian society. The population-based cancer registry of Victoria was used to describe the incidence of adenocarcinoma of the oesophagus and gastric cardia.

METHODS

Data were obtained from 1982 to 1991 and were analysed using the Poisson regression techniques.

RESULTS

In men, a statistically significant annual increase of 9.5% in oesophageal adenocarcinoma and a non-significant increase of 1.6% in adenocarcinoma of the gastric cardia was observed. These increases were balanced by decreases in other histological types found in the oesophagus in men resulting in little change in the overall rate. No significant trends by age or histological type were observed in women.

CONCLUSIONS

There is evidence for a rise in adenocarcinoma in men in Victoria. Possible risk factors include Barrett's oesophagus.

摘要

背景

有临床证据表明,澳大利亚社会中下段食管癌的发病率正在上升。利用维多利亚州基于人群的癌症登记处的数据来描述食管癌和贲门腺癌的发病率。

方法

获取1982年至1991年的数据,并使用泊松回归技术进行分析。

结果

在男性中,观察到食管腺癌每年有统计学意义的9.5%的增长,贲门腺癌有1.6%的非显著性增长。这些增长被男性食管中其他组织学类型的减少所平衡,导致总体发病率变化不大。在女性中未观察到按年龄或组织学类型的显著趋势。

结论

有证据表明维多利亚州男性的腺癌发病率有所上升。可能的危险因素包括巴雷特食管。

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