Ridder G J, Maschek H, Klempnauer J
Clinic for Abdiominal and Transplantation Surgery, Hanover Medical School, Hanover, Germany.
Eur J Surg Oncol. 1996 Jun;22(3):232-6. doi: 10.1016/s0748-7983(96)80008-4.
This report details nine patients after curative surgical resection of histologically proven mucinous cystadenocarcinoma of the pancreas and compares the prognosis with ductal adenocarcinomas. Cystadenocarcinomas represented 2.1% (10/ 466) of a total of 466 patients who underwent surgical exploration and 5.5%, of all curatively resected carcinomas of the exocrine pancreas at Hanover Medical School from 1971 to 1994. Forty percent of adenocarcinomas and 90% of cystadenocarcinomas were resectable. A curative R0 resection was possible in all patients with cystadenocarcinoma and 85 % with adenocarcinoma. Six of the patients with cystadenocarcinoma were female and three were male. Their median age was 54 +/- 12 years (range: 44 to 81 years). Four cystic neoplasms were located in the head, one in the head and body, three in the tail, and one in the body and tail of the pancreas. There was no hospital mortality in this group. The prognosis after resection of cystadenocarcinomas was significantly better compared to ductal adenocarcinomas of the pancreas. The Kaplan-Meier survival was 89% vs 52% after 1 year, and 56% vs 13% at 5 years. Our results indicate the favourable prognosis of cystadeno- over ductal adenocarcinomas of the pancreas in a cohort of patients with curative tumour resection.
本报告详细介绍了9例经组织学证实为胰腺黏液性囊腺癌且接受根治性手术切除的患者，并将其预后与导管腺癌进行了比较。在466例接受手术探查的患者中，囊腺癌占2.1%（10/466）；在1971年至1994年于汉诺威医学院接受根治性切除的所有外分泌性胰腺肿瘤患者中，囊腺癌占5.5%。40%的腺癌和90%的囊腺癌可切除。所有囊腺癌患者及85%的腺癌患者均可进行根治性R0切除。囊腺癌患者中6例为女性，3例为男性。他们的中位年龄为54±12岁（范围：44至81岁）。4例囊性肿瘤位于胰头，1例位于胰头和胰体，3例位于胰尾，1例位于胰体和胰尾。该组无医院死亡病例。与胰腺导管腺癌相比，囊腺癌切除后的预后明显更好。1年后的Kaplan-Meier生存率分别为89%和52%，5年后分别为56%和13%。我们的结果表明，在一组接受肿瘤根治性切除的患者中，胰腺囊腺癌的预后优于导管腺癌。
